Types of Hypersensitivity Reactions

  • Allergic (IgE) reactions are type I hypersensitivity reactions8,9
    • These reactions are mediated by IgE antibodies
  • When exposed to an allergen (a molecule causing an allergic reaction) the body mounts an IgE mediated response
    • Clinical symptoms occur within minutes (<2 hours)
    • They range from mild (allergic rhino-conjunctivitis, atopic eczema and gastrointestinal) to severe (asthma, anaphylactic shock the most severe) 9
  • Food IgG reactions are type III hypersensitivity reactions
    • These reactions are mediated by IgG antibodies
  • The body mounts an IgG mediated response
    • Characteristically the response is delayed, symptoms occurring within hours to days 2,7

Summary table showing Food IgE Allergy vs. Food IgG Reaction